Production environment and process of sterile bags.bag in box Processing

Aseptic bag, a new high-tech packaging material, is made from polyethylene particles through film blowing, cutting, heat sealing, Vacuum packing, sterilization and other processes in a clean environment

purpose

Sterile bags are widely used for the transportation and temporary storage of sterile solid raw materials, sterile pharmaceutical excipients, sterile preparations, and other products due to their sterile, non-toxic, excellent low-temperature resistance, good chemical stability, and electrical insulation properties, as well as the transit packaging of sterile rubber stoppers from cleaning to filling lines. In addition, in the food industry, sterile bags can also be combined with cardboard and aluminum foil to form packaging containers for food. The weight of sterile bags accounts for about 20% of the entire packaging, mainly preventing liquid leakage and microbial invasion.

Production environment and process

According to the new GMP standard, the production environment of sterile bags needs to be carried out in workshops with a cleanliness level of C or above. The cleanliness of the workshop needs to be graded based on the number of dust particles and settling bacteria in the workshop. A level is higher for Z, and the higher the level, the fewer dust particles and settling bacteria in the bag.

The production process of sterile bags mainly includes film blowing, cutting, heat sealing bag making, Vacuum packing and sterilization.

Blowing film: Firstly, open the air purification system in the workshop and disinfect the workshop and operators to ensure that the operating environment meets the set standards. Blow film the purified polyethylene particles at a certain temperature;

Cutting: The tubular film obtained after blowing is cut into different sizes of film cylinders according to customer requirements; Heat sealing bag making: use a heat sealing machine to seal the membrane cylinder;

Vacuum packing: multi-layer Vacuum packing shall be carried out according to a certain number of sealed sterile bags;

Sterilization: Sterilize the packaged sterile bag with gamma rays to meet the product's sterility requirements.

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